MS 및 LC/MS MassPREP™ 소모품을 사용하여 매트릭스 중의 다양한 biomolecule을 우수하고 재현성 높은 질량 분석 결과로 얻을 수 있습니다. 본 계열은 권장하는 분석법이 포함되어 있어 사용하기 쉽고 Waters의 엄격한 품질 제어 요건들을 충족하도록 제조되었습니다. 이러한 높은 순도의 표준품, 시약, MALDI 매트릭스 및 검량선용 시약(calibrant) 및 키트들은 편리하게 묶어서 사용하기 쉬운 형태로 제공됩니다.
Enzymate Online Digestion Columns
Provides fast and reproducible online protein digestion, shortens overall protein sample preparation time, and provides the ability to optimize protein digestion efficiency by changing temperature and flow rate.
Waters Enzymate BEH Pepsin Column: ◾Provides fast, reproducible, and efficient online protein digestion, typically within 30 seconds ◾Shortens overall protein sample preparation time ◾Offer the ability to optimize protein digestion efficiency by changing temperature and/or flow rate
Low and High Pressure Digestion Efficiency Comparisons
Shown on the right is the digestion efficiency comparison between low and high pressure digestions. The Waters Enzymate BEH Pepsin Column was used for digestion pressure at 1,000 psi (low) and 13,500 psi (high). Higher pressure digestion enhanced digestion efficiency.
ACQUITY UPLC M-Class HDX System
Hydrogen deuterium exchange mass spectrometry (HDX MS) is used to study a protein’s structural dynamics and conformational changes, a component of understanding a protein’s higher order structure. Information about protein conformation from an HDX MS study can be used to compare a control with an analyte by measuring the relative amount of deuteration uptake. HDX MS is capable of monitoring domain interaction, localized protein breathing, and folding or unfolding in the solution phase. The ACQUITY UPLC M-Class System can quantify small changes in protein conformation by extending its pressure range to enable a higher efficiency separation. An integral part of the ACQUITY UPLC M-Class HDX System is the Waters Enzymate BEH Pepsin Column which performs online protein digestion.